A new paradigm for treating transcription factor-driven cancers
In the current issue of Proceedings of the National Academy of Sciences, researchers from Nationwide Children's Hospital describe a new paradigm for treating transcription factor-driven cancers. The...
View ArticleHow genes and environment interact to raise risk of congenital heart defects
Infants of mothers with diabetes have a three- to five-fold increased risk of congenital heart defects. Such developmental defects are likely caused by a combination of genetic and environmental...
View ArticleNew study shows TBI laws effective at reducing rate of recurrent concussions
Since 2014, all 50 states and the District of Columbia have enacted one or more traumatic brain injury (TBI) laws, more commonly known as concussion laws. These laws often include mandates to remove...
View ArticleDoctors warn of a common respiratory illness in children
Like most moms, Shanisty Ireland had dealt with many bugs being passed between her three children. Last winter, she thought her newborn, Adam, had the same cold that had caused her older children to...
View ArticleTwo classes of GGAA-microsatellites in a Ewing sarcoma context
In a study published in PLOS ONE, researchers describe two types of GGAA-microsatellites and their roles in EWS/FLI binding and gene regulation in Ewing sarcoma. Ewing sarcoma is the second most common...
View ArticlePhase 1 study shows encouraging data for gene replacement therapy for SMA type I
A one-time intravenous infusion of the high dose of gene therapy extended the survival of patients with spinal muscular atrophy type 1 (SMA1) in a Phase 1 clinical trial, according to a study published...
View ArticleInjuries from window blinds send two children to the emergency department...
Most homes have them. They help keep our rooms warm or cold and even add a pop of color to tie the décor together. But window blinds can cause serious injuries or even death to young children. A new...
View ArticleTeens show decreased risk for heart disease later in life after bariatric...
Adolescents with severe obesity who had bariatric surgery showed significant improvements in cardiovascular disease risk factors, according to the most recent "Teen Longitudinal Assessment of Bariatric...
View ArticleNew study finds large increase in non-powder gun-related eye injuries
A new study conducted by researchers in the Center for Injury Research and Policy of the Research Institute at Nationwide Children's Hospital investigated sports- and recreation-related eye injuries...
View Article