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Pediatric clinic tests virtual reality for hemophilia patients during procedures

As a nurse clinician in the comprehensive hemophilia treatment center at Nationwide Children's Hospital for nearly 30 years, Charmaine Biega, RN, has watched her patients endure hundreds of needle...

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Two genes linked to postpartum immunity revival in women with persistent...

Alternative forms of two genes are associated with a boost in immunity to hepatitis C after childbirth, a study led by a Nationwide Children's Hospital physician-researcher shows.

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New study points to a possible cause of many preterm births

The discovery that small calcium deposits in fetal membranes may lead to a mother's water breaking prematurely suggests that dietary or other interventions could prevent those preterm births.

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Free 'Track it!' app tracks seizures on Apple Watch

Nationwide Children's Hospital and SeizureTracker.com are introducing a new wearable app to help track seizures called Track It! – available for the Apple Watch in the Apple Store today.

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Researchers encourage legislation that covers drivers of all ages to keep...

Distracted driving is a prevalent safety hazard for everyone, but especially for drivers in their first several years behind the wheel. A new study from the Center for Injury Research and Policy at The...

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Model demonstrates high-quality patient care while reducing costs

Providing high-quality patient care while reducing costs is a significant goal in the current health care reform environment. The Institute of Medicine has specifically called for the establishment of...

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Low back pain in school-aged children a common occurrence

Low back pain in school-aged children is a common occurrence, and the prevalence of low back pain increases once children reach school age - one percent at age seven years; six percent at age 10 years;...

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New study finds children and adolescents at risk from medicine intended for pets

Almost two thirds of households in the US own a pet and many of these households have children that either live in or visit the home. As pet owners know, it is common for pets to need medications...

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Two investigational antitumor agents work better together against MPNST and...

Two investigational agents, Aurora A kinase inhibitor (alisertib) and HSV1716, a virus derived from HSV-1 and attenuated by the deletion of RL1, have shown some antitumor efficacy in early clinical...

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Heart drug improves or stabilizes heart function in Duchenne muscular dystrophy

Researchers at The Ohio State University Ross Heart Hospital and Nationwide Children's Hospital have shown early treatment with the heart failure medication eplerenone can improve heart function in...

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Nursery product-related injuries on the rise among young children

Parents of young children use nursery products daily but these products are associated with injury more often than you might think. A new study from the Center for Injury Research and Policy at...

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Poison centers receive 32 calls a day about kids exposed to prescription opioids

A new study published online today by Pediatrics and conducted by the Center for Injury Research and Policy and the Central Ohio Poison Center at Nationwide Children's Hospital found that there were...

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Spine surgery helps girl with cerebral palsy walk

Bhoomi Manjunatha, age five, has been able to rely less on her walker and wheelchair, and more on her own two feet, because of a surgery performed at Nationwide Children's Hospital. Her hard work and...

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Cotton tip applicators are sending 34 kids to the emergency department each day

While cotton tip applicators can be used for household cleaning, crafts and applying cosmetics, they are unfortunately also causing injuries to children. A study conducted by Nationwide Children's...

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First study of Oncolytic HSV-1 in children and young adults with cancer...

HSV1716 - an oncolytic herpes simplex virus-1 - has been studied in adults via injection into the brain and superficial tumors. Now, a team of researchers at Nationwide Children's Hospital and...

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Lawn mower injuries send 13 children to the emergency department every day

On average every day in the United States, 13 children receive emergency treatment for a lawn mower-related injury. That adds up to almost 4800 children injured each year. A recent study from the...

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Immune profiling leads to implications for immunotherapy for NF1-associated...

Neurofibromatosis type 1 (NF1)—an autosomal dominant disorder affecting approximately one in every 3,500 people—results in dysfunctional neurofibromin, a protein expressed throughout the body and...

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Combining immunotherapies effective against mouse model of cancer

Rhabdomyosarcoma, a cancer made up of cells that normally develop into skeletal muscles, is the most common soft tissue cancer in children. If it is detected early and localized in certain areas,...

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Study finds rate of medication errors resulting in serious medical outcomes...

Every 21 seconds someone in the United States calls Poison Control because of a medication error. A new study from the Center for Injury Research and Policy and the Central Ohio Poison Center at...

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Team studies mechanism of H. influenzae biofilm formation

A research study identifying novel bacterial physiology in the creation of biofilms by Nationwide Children's Hospital scientists has been published in the current issue of Proceedings of the National...

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Study finds 275,000 calls to poison control centers for dietary supplement...

U.S. Poison Control Centers receive a call every 24 minutes, on average, regarding dietary supplement exposures, according to a new study from the Center for Injury Research and Policy and the Central...

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A new paradigm for treating transcription factor-driven cancers

In the current issue of Proceedings of the National Academy of Sciences, researchers from Nationwide Children's Hospital describe a new paradigm for treating transcription factor-driven cancers. The...

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How genes and environment interact to raise risk of congenital heart defects

Infants of mothers with diabetes have a three- to five-fold increased risk of congenital heart defects. Such developmental defects are likely caused by a combination of genetic and environmental...

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New study shows TBI laws effective at reducing rate of recurrent concussions

Since 2014, all 50 states and the District of Columbia have enacted one or more traumatic brain injury (TBI) laws, more commonly known as concussion laws. These laws often include mandates to remove...

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Doctors warn of a common respiratory illness in children

Like most moms, Shanisty Ireland had dealt with many bugs being passed between her three children. Last winter, she thought her newborn, Adam, had the same cold that had caused her older children to...

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Two classes of GGAA-microsatellites in a Ewing sarcoma context

In a study published in PLOS ONE, researchers describe two types of GGAA-microsatellites and their roles in EWS/FLI binding and gene regulation in Ewing sarcoma. Ewing sarcoma is the second most common...

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Phase 1 study shows encouraging data for gene replacement therapy for SMA type I

A one-time intravenous infusion of the high dose of gene therapy extended the survival of patients with spinal muscular atrophy type 1 (SMA1) in a Phase 1 clinical trial, according to a study published...

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Injuries from window blinds send two children to the emergency department...

Most homes have them. They help keep our rooms warm or cold and even add a pop of color to tie the décor together. But window blinds can cause serious injuries or even death to young children. A new...

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Teens show decreased risk for heart disease later in life after bariatric...

Adolescents with severe obesity who had bariatric surgery showed significant improvements in cardiovascular disease risk factors, according to the most recent "Teen Longitudinal Assessment of Bariatric...

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New study finds large increase in non-powder gun-related eye injuries

A new study conducted by researchers in the Center for Injury Research and Policy of the Research Institute at Nationwide Children's Hospital investigated sports- and recreation-related eye injuries...

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