Novel approach obtains protein signatures from host and pathogen with one...
A novel study from researchers at Nationwide Children's Hospital has shown that it is possible to obtain both host and bacteria protein signatures in a sample smaller than the average human biopsy. The...
View ArticleLoss of MHCI in motor neurons leads to ALS astrocyte toxicity
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a devastating progressive neurodegenerative disease that results in the death of motor neurons, the nerve cells that control...
View ArticleGray matter abnormality predicts neurodevelopmental problems in smaller...
Magnetic resonance imaging of the brain is increasingly used to predict neurodevelopmental outcomes in premature infants, but the existing systems of analyzing or "scoring" those MRIs rely heavily on...
View ArticleNew study finds skateboarding sent about 176 youth to US EDs every day
Skateboarding is a popular recreational sport and participation has increased the last several decades, faster than any other sport or recreation activity between 1998 and 2007. With growing...
View ArticleNew study finds laundry detergent packets more dangerous than other types of...
A new study conducted by the Center for Injury Research and Policy of the Research Institute at Nationwide Children's Hospital and the Central Ohio Poison Center found that exposure to laundry...
View ArticleFirst implantable hemodynamic monitoring device in single ventricle Fontan...
While the Fontan procedure has improved the short- and mid-term outcomes for patients born with single ventricle anatomy, long-term complications of Fontan circulation include heart failure. These...
View ArticleBabies fed directly from breast may be at less risk for ear infections
Feeding at the breast may be healthier than feeding pumped milk from a bottle for reducing the risk of ear infection, and feeding breast milk compared with formula may reduce the risk of diarrhea,...
View ArticleNew guidelines for nausea, stomach pain and other problems help physicians...
A child feels nauseated all the time, but no medical test can find what is wrong. Or a child vomits regularly, but there's no illness or eating disorder to explain it. These, and other stomach and...
View ArticleResearchers develop effective strategy for disrupting bacterial biofilms
Biofilms are communities of bacteria that adhere to a surface and are nearly impossible to eradicate when they are pathogenic, or disease-causing. Fortunately, a discovery from the laboratories of...
View ArticleResearchers describe new type of cancer therapy
A study conducted at Nationwide Children's Hospital has found that a new chemotherapy is effective against both pediatric and adult cancers, and that it allows other chemotherapies to more readily...
View ArticleFirst validated canine behavioral genetics findings of nine fear and...
Anxiety disorders are the most common type of mental illness in the United States. And while much is understood about the biochemistry of anxiety, little is known about the genetic variation associated...
View ArticleStudy finds average of two injuries every hour in the US from strollers,...
Although strollers and carriers are typically used to safely transport children, injuries do occur while using these products. A study conducted by the Center for Injury Research and Policy of the...
View ArticleNew study finds low transfer rates of pediatric burn patients in the US
According to a new study from researchers in the Center for Pediatric Trauma Research and the Center for Injury Research and Policy at Nationwide Children's Hospital, nearly 127,000 kids in the U.S had...
View ArticleNew chemotherapy and delivery small molecule is effective against multiple...
Open Therapeutics announces licensing a new class of anticancer drugs from Nationwide Children's Hospital. The drug, amphiphilic amines (RCn), shows promise against mouse models of cancer, including...
View ArticleStudy: Care providers underestimate pain during pediatric burn dressing change
Dressing changes have been identified as one of the major contributors to perceived pain during burn care, and so it is important that pain be assessed accurately. But a new study from the Center for...
View ArticleNew study finds rate of injuries among youth soccer players doubled
A new study, published online today in Pediatrics, found that from 1990 through 2014, the number of soccer-related injuries treated in hospital emergency departments in the US each year increased by 78...
View ArticleTeam finds relationship and behavioral differences between children and early...
According to the Centers for Disease Control and Prevention (CDC), suicide was the 10th leading cause of death for children ages 5 to 11 in 2014. This was the first time suicide had shown up in the...
View ArticleOligodendrocytes induce motor neuron death in ALS
A first-of-its-kind oligodendrocyte in vitro model shows that human cells normally supportive of motor neuron function play an active role in amyotrophic lateral sclerosis pathogenesis – and this...
View ArticleStudy finds exercise treadmills significant cause of hand burns in children
In recent years, home exercise equipment has become increasingly common, and treadmills have continued to be the largest selling exercise category by a large margin. However, this trend has also led to...
View ArticlePediatric clinic tests virtual reality for hemophilia patients during procedures
As a nurse clinician in the comprehensive hemophilia treatment center at Nationwide Children's Hospital for nearly 30 years, Charmaine Biega, RN, has watched her patients endure hundreds of needle...
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