Evidence supports blocking immune response to enhance viral therapy against...
Following several years of study, investigators have found more evidence that viral therapy to treat solid tumors can be enhanced by blocking the body's natural immune response.
View ArticleResearch reveals protective properties of influenza vaccines
(Medical Xpress)—Collaborating scientists from Nationwide Children's Hospital, Baylor Institute for Immunology Research, and Mount Sinai School of Medicine have identified an important mechanism for...
View ArticleAmusement rides injure 4,400+ kids a year
A new study by researchers in the Center for Injury Research and Policy of The Research Institute at Nationwide Children's Hospital examined injuries to children related to amusement rides, which...
View ArticleSummer sees a spike in chemical injuries in kids
Hydrocarbons, a chemical compound commonly found in household items from cleaning products to gasoline, are among the top 10 causes of pediatric poisoning deaths in the United States. A new study by...
View ArticleStudy shows preschoolers affected by medication-related poisonings at...
Poisonings in young children have increased over the past decade, mainly due to medications in the home. A new study led by the Central Ohio Poison Center at Nationwide Children's Hospital, found that...
View Article$1.6 million study of appendicitis treatment could help children avoid surgery
In the first study of its kind in the United States, researchers at Nationwide Children's Hospital will examine the effectiveness of antibiotic therapy alone to treat appendicitis in children, research...
View ArticleTechnique could identify patients at high risk of stroke or brain hemorrhage
Measuring blood flow in the brain may be an easy, noninvasive way to predict stroke or hemorrhage in children receiving cardiac or respiratory support through a machine called ECMO, according to a new...
View ArticleFirst pediatric-focused diabetes calculator
Nationwide Children's Hospital recently developed an online resource to help parents manage their child's diabetes more effectively and care for their health at home. The "Diabetes Calculator for...
View ArticleMultidisciplinary initiative reduces airway infection in pediatric intensive...
An initiative that combines a multidisciplinary health care approach with a range of preventive measures could cut the rate of a common airway infection among children in intensive care by more than...
View ArticleStudy finds missing piece of pediatric cancer puzzle
Most of the time, it takes decades of accumulating genetic errors for a tumor to develop. While this explains the general occurrence of cancer in adults, it leaves a gap in understanding of the cause...
View ArticleResearchers identify genetic mutation linked to congenital heart disease
A mutation in a gene crucial to normal heart development could play a role in some types of congenital heart disease—the most common birth defect in the U.S. The finding, from a team in The Research...
View ArticleNew study finds increase in nonfatal food-related choking among children in...
Choking is a leading cause of injury among children, especially for children 4 years of age and younger. A new study by researchers at the Center for Injury Research and Policy of The Research...
View ArticleParents don't fully understand biobank research, study finds
Researchers who collect genetic samples from children for medical research need to explain the process more clearly to parents, according to a new study that suggests many parents don't fully...
View ArticleNew initiative could help improve surgical outcomes in children, study suggests
A group of pediatric surgeons at hospitals around the country have designed a system to collect and analyze data on surgical outcomes in children – the National Surgical Quality Improvement Program...
View ArticleChronic illness puts pediatric trauma patients at higher risk
In a recent study published in the Journal of Trauma and Acute Care Surgery, researchers from the Center for Injury Research and Policy in The Research Institute at Nationwide Children's Hospital found...
View ArticleNew drug improves walking performance for Duchenne muscular dystrophy patients
Results from a clinical trial of eteplirsen, a drug designed to treat Duchenne muscular dystrophy, suggest that the therapy allows participants to walk farther than people treated with placebo and...
View ArticleCombined therapy could repair and prevent damage in Duchenne muscular dystrophy
New research on two promising gene therapies suggests that combining them into one treatment not only repairs muscle damage caused by Duchenne muscular dystrophy, but also prevents future injury from...
View ArticleHB-EGF protects intestines from a variety of injuries, pair of studies suggests
It's not often that one treatment offers therapeutic potential for multiple conditions. However, after more than two decades of research, Gail Besner, MD, principal investigator for the Center for...
View ArticleStudy examines ways to restore immunity to chronic hepatitis C infection
The hepatitis C virus hijacks the body's immune system, leaving T cells unable to function. A new study in animal models suggests that blocking a protein that helps the virus thrive could restore...
View ArticleMegabladder mouse model may help predict severity of pediatric kidney damage
A new study of the megabladder mouse model suggests that tracking changes in the expression of key genes involved in kidney disease could help physicians predict the severity of urinary tract...
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